Design new small-molecule binders with Boltz. Use when generating novel ligands or hits for a target without a fixed compound library. Not for screening existing molecules or one-off docking.
Install
npx skills add boltz-bio/boltz-api-skills --skill boltz-small-molecule-designnpx skills add boltz-bio/boltz-api-skills --skill boltz-small-molecule-design -a claude-code -gnpx skills add boltz-bio/boltz-api-skills --skill boltz-small-molecule-design -a codex -ggemini skills install https://github.com/boltz-bio/boltz-api-skills.git --path skills/boltz-small-molecule-designgh skill install boltz-bio/boltz-api-skills boltz-small-molecule-designgit clone --depth 1 https://github.com/boltz-bio/boltz-api-skills /tmp/boltz-bio__boltz-api-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/boltz-bio__boltz-api-skills/skills/boltz-small-molecule-design ~/.claude/skills/boltz-small-molecule-design # Claude Code
cp -R /tmp/boltz-bio__boltz-api-skills/skills/boltz-small-molecule-design ~/.agents/skills/boltz-small-molecule-design # Codex, Cursor, Gemini CLI, Copilot, OpenCode