Protein language models through the EvolutionaryScale `esm` Python SDK. Generate and embed sequences with ESM3 (multimodal sequence, structure and function prompting), extract per-residue and mean-pooled embeddings with ESM C, fold sequences with ESMFold2, and run inference locally or against the Forge and Biohub hosted clients.
Install
npx skills add K-Dense-AI/drug-discovery-agent-skills --skill esmnpx skills add K-Dense-AI/drug-discovery-agent-skills --skill esm -a claude-code -gnpx skills add K-Dense-AI/drug-discovery-agent-skills --skill esm -a codex -ggemini skills install https://github.com/K-Dense-AI/drug-discovery-agent-skills.git --path skills/esmgh skill install K-Dense-AI/drug-discovery-agent-skills esmgit clone --depth 1 https://github.com/K-Dense-AI/drug-discovery-agent-skills /tmp/K-Dense-AI__drug-discovery-agent-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/K-Dense-AI__drug-discovery-agent-skills/skills/esm ~/.claude/skills/esm # Claude Code
cp -R /tmp/K-Dense-AI__drug-discovery-agent-skills/skills/esm ~/.agents/skills/esm # Codex, Cursor, Gemini CLI, Copilot, OpenCode