Analyzes pooled CRISPR screen FASTQ reads and guide-count matrices with MAGeCK, validates guide libraries and contrasts, measures replicate and library QC, and produces gene hit rankings with effect sizes and FDR. Use for new knockout, CRISPRi, or CRISPRa screen analysis, enrichment or depletion contrasts, and MAGeCK count/test workflows; existing public dependency-score lookup belongs to DepMap.
Install
npx skills add K-Dense-AI/scientific-agent-skills --skill magecknpx skills add K-Dense-AI/scientific-agent-skills --skill mageck -a claude-code -gnpx skills add K-Dense-AI/scientific-agent-skills --skill mageck -a codex -ggemini skills install https://github.com/K-Dense-AI/scientific-agent-skills.git --path skills/mageckgh skill install K-Dense-AI/scientific-agent-skills mageckgit clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills /tmp/K-Dense-AI__scientific-agent-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/K-Dense-AI__scientific-agent-skills/skills/mageck ~/.claude/skills/mageck # Claude Code
cp -R /tmp/K-Dense-AI__scientific-agent-skills/skills/mageck ~/.agents/skills/mageck # Codex, Cursor, Gemini CLI, Copilot, OpenCode