Run RFD4-Proteina NIM for joint protein structure and sequence design, conditioned generation, and reward-guided search using the NVIDIA hosted API or a self-hosted NIM. Not for the older RFdiffusion contigs API.
Install
npx skills add NVIDIA/skills --skill rfd4-proteina-nimnpx skills add NVIDIA/skills --skill rfd4-proteina-nim -a claude-code -gnpx skills add NVIDIA/skills --skill rfd4-proteina-nim -a codex -ggemini skills install https://github.com/NVIDIA/skills.git --path skills/bionemo-rfd4-proteina-nimgh skill install NVIDIA/skills rfd4-proteina-nimgit clone --depth 1 https://github.com/NVIDIA/skills /tmp/NVIDIA__skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/NVIDIA__skills/skills/bionemo-rfd4-proteina-nim ~/.claude/skills/rfd4-proteina-nim # Claude Code
cp -R /tmp/NVIDIA__skills/skills/bionemo-rfd4-proteina-nim ~/.agents/skills/rfd4-proteina-nim # Codex, Cursor, Gemini CLI, Copilot, OpenCode