Generate protein backbones using RFdiffusion, a diffusion-based generative model for de novo protein structure generation. Use this skill when: (1) Designing binder scaffolds for a target protein, (2) Generating novel protein backbones from scratch, (3) Scaffolding functional motifs into new proteins, (4) Specifying hotspot residues for interface design, (5) Creating symmetric oligomers.
Install
npx skills add adaptyvbio/protein-design-skills --skill rfdiffusionnpx skills add adaptyvbio/protein-design-skills --skill rfdiffusion -a claude-code -gnpx skills add adaptyvbio/protein-design-skills --skill rfdiffusion -a codex -ggemini skills install https://github.com/adaptyvbio/protein-design-skills.git --path skills/rfdiffusiongh skill install adaptyvbio/protein-design-skills rfdiffusiongit clone --depth 1 https://github.com/adaptyvbio/protein-design-skills /tmp/adaptyvbio__protein-design-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/adaptyvbio__protein-design-skills/skills/rfdiffusion ~/.claude/skills/rfdiffusion # Claude Code
cp -R /tmp/adaptyvbio__protein-design-skills/skills/rfdiffusion ~/.agents/skills/rfdiffusion # Codex, Cursor, Gemini CLI, Copilot, OpenCode