Assemble the human genetic evidence for and against a target before a programme commits to it — the evidence class that most improves the odds of surviving clinical development. Use this skill to pull gnomAD constraint metrics (LOEUF, pLI, observed/expected) that show whether loss of function is tolerated in people, retrieve GWAS Catalog associations and fine-mapped credible sets for a gene, and…
Install
npx skills add K-Dense-AI/drug-discovery-agent-skills --skill target-safetynpx skills add K-Dense-AI/drug-discovery-agent-skills --skill target-safety -a claude-code -gnpx skills add K-Dense-AI/drug-discovery-agent-skills --skill target-safety -a codex -ggemini skills install https://github.com/K-Dense-AI/drug-discovery-agent-skills.git --path skills/target-safetygh skill install K-Dense-AI/drug-discovery-agent-skills target-safetygit clone --depth 1 https://github.com/K-Dense-AI/drug-discovery-agent-skills /tmp/K-Dense-AI__drug-discovery-agent-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/K-Dense-AI__drug-discovery-agent-skills/skills/target-safety ~/.claude/skills/target-safety # Claude Code
cp -R /tmp/K-Dense-AI__drug-discovery-agent-skills/skills/target-safety ~/.agents/skills/target-safety # Codex, Cursor, Gemini CLI, Copilot, OpenCode