Discover novel small molecule binders for protein targets using structure-based and ligand-based approaches. Creates actionable reports with candidate compounds, ADMET profiles, and synthesis feasibility. Use when users ask to find small molecules for a target, identify novel binders, perform virtual screening, or need hit-to-lead compound identification.
Install
npx skills add mims-harvard/ToolUniverse --skill tooluniverse-binder-discoverynpx skills add mims-harvard/ToolUniverse --skill tooluniverse-binder-discovery -a claude-code -gnpx skills add mims-harvard/ToolUniverse --skill tooluniverse-binder-discovery -a codex -ggemini skills install https://github.com/mims-harvard/ToolUniverse.git --path skills/tooluniverse-binder-discoverygh skill install mims-harvard/ToolUniverse tooluniverse-binder-discoverygit clone --depth 1 https://github.com/mims-harvard/ToolUniverse /tmp/mims-harvard__ToolUniverse
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/mims-harvard__ToolUniverse/skills/tooluniverse-binder-discovery ~/.claude/skills/tooluniverse-binder-discovery # Claude Code
cp -R /tmp/mims-harvard__ToolUniverse/skills/tooluniverse-binder-discovery ~/.agents/skills/tooluniverse-binder-discovery # Codex, Cursor, Gemini CLI, Copilot, OpenCode