Alterlab Ligandmpnn

AlterLab Creative Technologies Laboratory

Design protein sequences around bound ligands, metals, and nucleic acids with LigandMPNN (Dauparas 2023) — inverse folding that conditions on non-protein context, so binding-pocket and metal-site residues are chosen to fit the actual ligand.

Install

npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-ligandmpnn

npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-ligandmpnn -a claude-code -g

npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-ligandmpnn -a codex -g

gemini skills install https://github.com/AlterLab-IEU/AlterLab-Academic-Skills.git --path skills/bioinformatics/alterlab-ligandmpnn

gh skill install AlterLab-IEU/AlterLab-Academic-Skills alterlab-ligandmpnn

git clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills /tmp/AlterLab-IEU__AlterLab-Academic-Skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/AlterLab-IEU__AlterLab-Academic-Skills/skills/bioinformatics/alterlab-ligandmpnn ~/.claude/skills/alterlab-ligandmpnn   # Claude Code
cp -R /tmp/AlterLab-IEU__AlterLab-Academic-Skills/skills/bioinformatics/alterlab-ligandmpnn ~/.agents/skills/alterlab-ligandmpnn   # Codex, Cursor, Gemini CLI, Copilot, OpenCode

Install

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