Co-fold biomolecular complexes with Boltz-2, an open AlphaFold3-style model — predict protein + ligand (SMILES/CCD), protein + nucleic-acid, and multi-chain structures in one pass, with binding-affinity prediction. Use when folding a protein together with a small-molecule ligand, predicting a holo (ligand-bound) complex or its binding affinity, or co-folding protein–DNA/RNA assemblies.
安装
npx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-boltznpx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-boltz -a claude-code -gnpx skills add AlterLab-IEU/AlterLab-Academic-Skills --skill alterlab-boltz -a codex -ggemini skills install https://github.com/AlterLab-IEU/AlterLab-Academic-Skills.git --path skills/bioinformatics/alterlab-boltzgh skill install AlterLab-IEU/AlterLab-Academic-Skills alterlab-boltzgit clone --depth 1 https://github.com/AlterLab-IEU/AlterLab-Academic-Skills /tmp/AlterLab-IEU__AlterLab-Academic-Skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/AlterLab-IEU__AlterLab-Academic-Skills/skills/bioinformatics/alterlab-boltz ~/.claude/skills/alterlab-boltz # Claude Code
cp -R /tmp/AlterLab-IEU__AlterLab-Academic-Skills/skills/bioinformatics/alterlab-boltz ~/.agents/skills/alterlab-boltz # Codex, Cursor, Gemini CLI, Copilot, OpenCode