Solubility-optimized protein sequence design using SolubleMPNN. Use this skill when: (1) Designing for E. coli expression, (2) Optimizing solubility of designed proteins, (3) Reducing aggregation propensity, (4) Need high-yield expression, (5) Avoiding inclusion body formation. For standard design, use proteinmpnn. For ligand-aware design, use ligandmpnn.
安装
npx skills add adaptyvbio/protein-design-skills --skill solublempnnnpx skills add adaptyvbio/protein-design-skills --skill solublempnn -a claude-code -gnpx skills add adaptyvbio/protein-design-skills --skill solublempnn -a codex -ggemini skills install https://github.com/adaptyvbio/protein-design-skills.git --path skills/solublempnngh skill install adaptyvbio/protein-design-skills solublempnngit clone --depth 1 https://github.com/adaptyvbio/protein-design-skills /tmp/adaptyvbio__protein-design-skills
mkdir -p ~/.claude/skills ~/.agents/skills
cp -R /tmp/adaptyvbio__protein-design-skills/skills/solublempnn ~/.claude/skills/solublempnn # Claude Code
cp -R /tmp/adaptyvbio__protein-design-skills/skills/solublempnn ~/.agents/skills/solublempnn # Codex, Cursor, Gemini CLI, Copilot, OpenCode